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Contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI) is one of the major adverse outcomes affecting the prognosis of patients with acute ST-segment elevation myocardial infarction (STEMI). Ischemic postconditioning prior to PCI (pre-PCI) in patients with STEMI is hypothesized to be protective against CIN after PCI.. activities and the embedded sensors collect data on cardiopulmonary. rate in detecting hypoxia. Stickler et al reported wide phenotypic variability, which often resulted in delayed or missed diagnosis in many cases. Certain clinical findings, however, are consistent: 95% ocular problems (retinal detachment in 60%, myopia in 90%, and blindness in 4%); 84% facial abnormalities (flat nose, small mandible, or cleft palate); 70% hearing loss; 90% degenerative joint disease and pain. Stickler syndrome is an autosomal dominant disease characterized by midfacial flattening and variable disorders of vision, hearing and articulation. There is great diversity and severity of pathologic articular conditions in patients with Stickler syndrome. Most patients are recognized in childhood if they present with cleft palate or severe ocular findings or have a positive family history. Approximately one fourth has an open cleft palate, and other patients have more subtle clefting (bifid ovula or submucus clefts) [1,2].

Stickler et al reported wide phenotypic variability, which often resulted in delayed or missed diagnosis in many cases. Certain clinical findings, however, are consistent: 95% ocular problems (retinal detachment in 60%, myopia in 90%, and blindness in 4%); 84% facial abnormalities (flat nose, small mandible, or cleft palate); 70% hearing loss; 90% degenerative joint disease and pain. Stickler syndrome is an autosomal dominant disease characterized by midfacial flattening and variable disorders of vision, hearing and articulation. There is great diversity and severity of pathologic articular conditions in patients with Stickler syndrome. Most patients are recognized in childhood if they present with cleft palate or severe ocular findings or have a positive family history. Approximately one fourth has an open cleft palate, and other patients have more subtle clefting (bifid ovula or submucus clefts) [1,2].. A 3-year retrospective study was carried out on 268 subjects. The study included 68 patients with moderate-to-severe psoriasis, screened for latent tuberculosis infection (LTBI) and subjects without psoriasis (100 adults and 100 children) with close contact with infected individuals..

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